Peter E Lobie Selected Research

Human Growth Hormone (Saizen)

11/2017	Autocrine hGH stimulates oncogenicity, epithelial-mesenchymal transition and cancer stem cell-like behavior in human colorectal carcinoma.
6/2017	Autocrine Human Growth Hormone Promotes Invasive and Cancer Stem Cell-Like Behavior of Hepatocellular Carcinoma Cells by STAT3 Dependent Inhibition of CLAUDIN-1 Expression.
5/2016	Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma.
1/2016	WNT4 mediates the autocrine effects of growth hormone in mammary carcinoma cells.
9/2015	Autocrine human growth hormone stimulates the tumor initiating capacity and metastasis of estrogen receptor-negative mammary carcinoma cells.
5/2015	Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer.
10/2011	Tumor expression of human growth hormone and human prolactin predict a worse survival outcome in patients with mammary or endometrial carcinoma.
8/2011	Autocrine human growth hormone reduces mammary and endometrial carcinoma cell sensitivity to mitomycin C.
9/2010	STAT3alpha is oncogenic for endometrial carcinoma cells and mediates the oncogenic effects of autocrine human growth hormone.
3/2009	Autocrine human growth hormone promotes tumor angiogenesis in mammary carcinoma.

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Peter E Lobie Research Topics

Disease

55	Neoplasms (Cancer) 02/2022 - 10/2006
51	Breast Neoplasms (Breast Cancer) 04/2022 - 07/2002
38	Carcinoma (Carcinomatosis) 01/2022 - 07/2002
18	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2011
9	Endometrial Neoplasms (Endometrial Cancer) 09/2017 - 08/2008
8	Hepatocellular Carcinoma (Hepatoma) 07/2017 - 07/2011
4	Carcinogenesis 01/2021 - 08/2015
4	Lymphatic Metastasis 01/2019 - 10/2011
3	Disease Progression 01/2021 - 06/2014
3	Triple Negative Breast Neoplasms 11/2017 - 01/2015
2	Pancreatic Neoplasms (Pancreatic Cancer) 03/2022 - 10/2018
2	Ovarian Epithelial Carcinoma 02/2022 - 01/2022
2	Ovarian Neoplasms (Ovarian Cancer) 01/2021 - 12/2020
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 12/2019
2	Adenocarcinoma of Lung 11/2019 - 05/2015
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2019 - 05/2015
2	Stomach Neoplasms (Stomach Cancer) 01/2018 - 05/2016
1	Lung Neoplasms (Lung Cancer) 01/2019
1	Inflammation (Inflammations) 01/2019

Drug/Important Bio-Agent (IBA)

17	Estrogen ReceptorsIBA 04/2022 - 12/2010
17	Human Growth Hormone (Saizen)FDA LinkGeneric 11/2017 - 07/2002
14	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2002
12	Trefoil Factor-3IBA 03/2022 - 12/2010
12	MicroRNAs (MicroRNA)IBA 12/2018 - 07/2011
11	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2011
11	Messenger RNA (mRNA)IBA 01/2021 - 01/2007
9	Tamoxifen FDA LinkGeneric 01/2022 - 12/2010
8	LigandsIBA 03/2022 - 06/2010
8	Estrogens (Estrogen)FDA Link 01/2022 - 12/2010
8	Small Interfering RNA (siRNA)IBA 05/2015 - 06/2005
5	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2021 - 06/2010
5	Hormones (Hormone)IBA 01/2018 - 10/2006
5	Cadherins (E-Cadherin)IBA 05/2016 - 03/2006
5	Growth Hormone (Somatotropin)IBA 01/2016 - 10/2006
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 02/2003
4	ProlactinIBA 01/2017 - 10/2011
4	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 09/2016 - 07/2011
4	Transcription Factors (Transcription Factor)IBA 08/2015 - 06/2013
3	Long Noncoding RNAIBA 01/2022 - 12/2017
3	Estrogen Receptor Modulators (Antiestrogen)IBA 01/2022 - 01/2011
3	4-nitrophenethyl bromide (NPB)IBA 10/2021 - 10/2018
3	Phosphotransferases (Kinase)IBA 01/2021 - 05/2005
3	Pharmaceutical PreparationsIBA 12/2020 - 01/2018
3	Biological ProductsIBA 01/2019 - 12/2014
3	Epidermal Growth Factor (EGF)IBA 06/2013 - 10/2011
3	Fibronectins (Fibronectin)IBA 01/2012 - 10/2004
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2012 - 03/2009
2	Estrogen Receptor alphaIBA 01/2022 - 01/2018
2	Fulvestrant (Faslodex)FDA Link 01/2022 - 12/2010
2	PlatinumIBA 01/2022 - 12/2020
2	3' Untranslated Regions (3' UTR)IBA 01/2021 - 01/2014
2	Carrier Proteins (Binding Protein)IBA 01/2021 - 10/2011
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021 - 01/2017
2	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 12/2019
2	Caspase 3 (Caspase-3)IBA 10/2018 - 12/2014
2	ClaudinsIBA 11/2017 - 01/2011
2	Phenobarbital (Luminal)FDA Link 10/2017 - 09/2017
2	Trastuzumab (Herceptin)FDA Link 09/2017 - 06/2014
2	matrigelIBA 06/2017 - 01/2012
2	azaspiraneIBA 09/2016 - 12/2014
2	AgarIBA 08/2015 - 02/2003
2	Complementary DNA (cDNA)IBA 05/2015 - 06/2014
2	Janus KinasesIBA 12/2014 - 01/2005
2	Prolactin Receptors (Prolactin Receptor)IBA 12/2012 - 04/2011
2	VimentinIBA 01/2012 - 10/2004
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 04/2022
1	UracilIBA 04/2022
1	AmidesIBA 04/2022
1	ThiouracilIBA 04/2022
1	CXC ChemokinesIBA 02/2022
1	ChemokinesIBA 02/2022
1	OxadiazolesIBA 01/2022
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022
1	palbociclibIBA 01/2022
1	Phenol (Carbolic Acid)FDA Link 10/2021
1	Aligeron (AS 2)IBA 10/2021
1	benzaldehydeIBA 10/2021
1	SolventsIBA 10/2021
1	AminesIBA 02/2021
1	diphenyl (biphenyl)IBA 02/2021
1	ParaffinIBA 01/2021
1	Poly CIBA 01/2021
1	Oncogene Proteins (Oncogene Protein)IBA 01/2021
1	Cisplatin (Platino)FDA LinkGeneric 12/2020
1	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 11/2020
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2020
1	abemaciclibIBA 01/2020
1	Carbon Nanotubes (Carbon Nanotube)IBA 01/2019
1	deguelinIBA 01/2019
1	AnthracyclinesIBA 01/2019
1	N-cyclopentyl-3-((4-(2,3-dichlorophenyl) piperazin-1-yl) (2-hydroxyphenyl) methyl) benzamideIBA 10/2018
1	Apoptosis Regulatory ProteinsIBA 10/2018
1	Large Neutral Amino Acid-Transporter 1IBA 01/2018
1	Cytotoxins (Cytolysins)IBA 01/2018
1	PyrimidinesIBA 01/2018
1	Proline (L-Proline)FDA Link 01/2018

Therapy/Procedure

16	Therapeutics 01/2022 - 01/2011
5	Drug Therapy (Chemotherapy) 12/2020 - 08/2011
4	Precision Medicine 02/2022 - 12/2020
1	Combination Drug Therapy (Combination Chemotherapy) 01/2019